Four-year survival after trans-jugular intrahepatic porto-systemic shunt for veno-occlusive disease following autologous bone marrow transplantation |
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Authors: | Annaloro Claudio Robbiolo Livia Pozzoli Ermanno Ibatici Adalberto Nicolini Antonio Salerno Francesco Deliliers Giorgio Lambertenghi |
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Affiliation: | Department of Hematology, Ospedale Maggiore di Milano, IRCCS, Via F Sforza, 35 - 20122 Milano, Italy. |
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Abstract: | Severe hepatic veno-occlusive disease is still a potentially lethal complication after bone marrow transplantation. We here report the case of a patient who developed liver veno-occlusive disease with severe hemodynamic dysfunction and was successfully treated by means of a trans-jugular intrahepatic portosystemic shunt. After three years, he is still disease-free with a functioning shunt and a normal laboratory liver profile. A trans-jugular intrahepatic portosystemic shunt is a treatment option that has been used in very few patients affected by hepatic veno-occlusive disease; its indications and timing remain to be established. |
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