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Synthesis of novel 1,4-naphthoquinone derivatives: antibacterial and antifungal agents |
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| Authors: | Cemil Ibis Amac Fatih Tuyun Hakan Bahar Sibel Sahinler Ayla Maryna V. Stasevych Rostyslav Ya. Musyanovych Olena Komarovska-Porokhnyavets Volodymyr Novikov |
| Affiliation: | 1. Department of Chemistry, Engineering Faculty, Istanbul University, Istanbul, Turkey 2. Department of Chemical Engineering, Engineering and Architecture Faculty, Beykent University, Istanbul, Turkey 3. Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, National University “Lviv Polytechnic”, Lviv, Ukraine |
| Abstract: | A novel series of substituted 1,4-naphthoquinone derivatives was synthesized and evaluated for antibacterial and antifungal activity. The structures of the novel products were characterized by spectroscopic methods. Among the tested compounds, 3a and 9 are the most effective compounds against M. luteum as potent antibacterial and C. tenuis and A. niger as potent antifungal. These two compounds are promising as biologically active compounds. |
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