| Protective Effect and Mechanism of Kuntai Capsule on Angiotensin Ⅱ-Induced Hypertension in Ovariectomized Rats |
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| 作者姓名： | GE Xiao-fen LI Sha-sha LIU Yan-hua LU Mei-qiu SU Hui-na YANG Xin SUN Xiao-wan |
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| 作者单位： | 1. Department of Obstetrics and Gynecology, Peking University People's Hospital;2. Department of Obstetrics and Gynecology, Dongying People's Hospital |
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| 摘 要： | Objective: To explore the protective effect and mechanism of Kuntai(KT) Capsule on angiotensin Ⅱ(AngⅡ)-induced hypertension in ovariectomized(OVX) rats. Methods: Fifty-four rats were randomly divided into 6 groups according to a random number table, 9 in each group: control, OVX sham+AngⅡ, OVX, OVX+AngⅡ,OVX+AngⅡ+E2, and OVX+AngⅡ+KT. OVX rats model was constructed by retroperitoneal bilateral ovariectomy.After 4 weeks of pretreatment with KT Capsule [0.8 g/(kg·d) and 17-β-estradiol(E2, 1.2 mg/(kg...
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