18F-FDG PET/CT与3.0T MRI联合显像在乳腺癌原发病灶诊断中的价值

目的 探讨18F-FDG PET/CT与3.0T MRI联合显像在乳腺癌原发病灶诊断中的价值。 方法 对38例临床怀疑为乳腺癌的女性患者于一周内分别行18F-FDG PET/CT、3.0T MRI和病理学检查。 结果 组织病理学检查结果证实，全部患者中，24例为乳腺癌患者，14例为乳腺良性肿瘤患者。3.0T MRI诊断乳腺癌的灵敏度、特异度、准确率分别为91.7%、78.6%、86.8%；PET/CT诊断乳腺癌的灵敏度、特异度、准确率分别为87.5%、92.9%、89.5%；PET/CT和3.0T MR联合显像诊断乳腺癌的灵敏度、特异度、准确率分别为100.0%、92.9%、97.4%；3种显像方法间灵敏度、特异度、准确率差异无统计学意义（χ2=2.987、1.612和2.955，P均＞0.05）。 结论 18F-FDG PET/CT和3.0T MRI联合显像在乳腺癌原发病灶诊断中具有重要价值；但与单独18F-FDG PET/CT和3.0T MRI显像比较，3种显像方法在乳腺癌原发病灶的诊断效能上差异无统计学意义。

Diagnosis value of 18F-FDG PET/CT and 3.0T MRI combined imaging in detecting the primary focus of breast cancer

Objective To explore the diagnosis value of 18F-FDG PET/CT and 3.0T MR combined imaging in detecting the primary focus of breast cancer. Methods Thirty eight female patients with highly suspected breast cancer were selected, 18F-FDG PET/CT and 3.0T MRI imaging were performed and their pathological results were gotten within 7 days. Results Twenty four malignant cases and 14 benign cases of the 38 patients were proved by pathology. The sensitivity, specificity and accuracy rate obtained by 3.0T MRI were 91.7%, 78.6% and 86.8%, respectively; they were 87.5%, 92.9% and 89.5% for 18F-FDG PET/CT; and which were 100.0%, 92.9% and 97.4% with 18F-FDG PET/CT and 3.0T MRI combined imaging. There were no significant difference among the three methods in the diagnostic ability(χ2=2.987, 1.612 and 2.955, all P > 0.05). Conclusions The combination of 18F-FDG PET/CT imaging and 3.0T MRI imaging in detecting the primary focus of breast cancer has important value, and comparison with separate 18F-FDG PET/CT imaging or 3.0T MRI imaging, the diagnosis efficiency of three imaging methods in breast cancer without statistics difference.