Malignant Lesions Initially Categorized as Probably Benign Breast Lesions: Retrospective Review of Ultrasonographic,Clinical and Pathologic Characteristics |
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Authors: | Hee Jung Moon Min Jung KimJin Young Kwak Jung Hyun YoonSoo Jin Kim Yu-Mee SohnEun-Kyung Kim |
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Institution: | Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, South Korea |
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Abstract: | The primary objective of this study was to review the ultrasonographic features of BI-RADS category 3 (“probably benign”) lesions that eventually proved to be malignant. A second objective was to investigate their clinical and pathologic features according to their palpability and time of biopsy. Thirty-two (0.8%) of 4000 women with lesions that were initially classified as “probably benign” proved to be malignant and formed the study group. The most common reason for a false negative assessment on ultrasound was a failure to recognize suspicious margin characteristics (28 of 32 malignancies, 87.5%). Malignancy was more frequent in palpable (2.4%, 21 of 859) than nonpalpable lesions (0.4%, 11 of 3141, p < 0.001). There was no statistical difference in the mean age, mean size of lesions, or tumor stage between patients who underwent early biopsy (n = 19) or biopsy after 6 months (n = 13). Twenty-nine of the lesions (90.6%) were retrospectively recategorized as BI-RADS 4, which calls for early biopsy. BI-RADS 3 lesions require especially careful assessment. (E-mail: ekkim@yuhs.ac) |
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Keywords: | BI-RADS Probably benign finding Breast malignancy Ultrasonography |
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