百蕊草药材内在品质研究

目的:研究百蕊草药材内在品质.方法:以总黄酮、山柰酚、甘露醇、多糖等多种活性成分为评价指标,系统研究不同居群、不同生长期、不同储存时间百蕊草药材内在品质.结果:百蕊草药材总黄酮质量分数3.38%,山柰酚0.984 7 mg·g-1,甘露醇6.12%,多糖14.08%,水溶性浸出物30.28%.不同居群百蕊草主要化学成分相似,但含量存在差异或显著差异；除多糖外,不同生长期百蕊草各化学成分含量呈下降趋势；随储存时间的延长,百蕊草药材总黄酮、山柰酚、甘露醇、多糖及浸出物等成分含量呈下降趋势.结论:在制定百蕊草质量标准时,应以总黄酮、山柰酚、甘露醇、多糖和浸出物等含量为主要成分指标.

Study on quality of medicinal material of Thesium chinense

Objective : To study the quality of medicinal material of Thesium chinense. Method : The active ingredients of total flavonoids, kaempferol, mannitol, polysaccharides were selected as the evaluative indicators to comprehensively evaluate the quality of medicinal material of T. chinense. Result : The total flavone 3.38%, kaempferol 0.984 7 mg·g^-1, mannitol 6.12%, polysaccharides 14.08% and water soluble extract 30.28% were measured in the sample of T. chinense. There was a certain correlation among these selected active ingredients. The compositions of most biological activities component in T. chinense of different populations were similar, but the contents were different significantly. The content of activities component in T. chinense showed a general tendency of declining during growth period and with the increase time of storage. Conclusion : Flavone, kaempferol, mannitol, polysaccharides should be selected as the indicators to evaluate the quality of medicinal material of T. chinense.