窄谱中波紫外线联合雷公藤片治疗156例手部湿疹疗效观察

目的：观察窄谱中波紫外线（NB—UVB）与雷公藤片联合治疗手部湿疹的疗效及不良反应。方法：采用开放对照研究方法，将156例患者分为A、B两组。A组80人给予雷公藤片，B组76人给予NB—UVB皮损照射＋口服雷公藤片治疗，疗程4周。结果：治疗结束时与治疗前比较，A组患者瘙痒、皮损、部位的积分和总积分分别下降70％、73．1％、70．5％和71％；而B组下降87．1％、91．7％、88．3％和89．1％。治疗前后组内比较及治疗后组间比较，其平均积分差异均有统计学意义（P〈0．05）。治疗过程中未见NB—UVB局部照射的不良反应，雷公藤片口服组主要副作用是：5％患者血白细胞减少、5％女性月经量减少，3．8％患者AST一过性升高，但都为自限性。结论：NB—UVB照射联合雷公藤片治疗手部湿疹可以提高疗效、缩短疗程、安全性好，值得临床选用。

Analysis on Effect of NB-UVB Combined with Tripterygium Glycoside on 156 Patients with Hand Eczema Treated

Objective:To study the effect on hand eczema treated with Narrow-band(NB) UVB and Tripterygium Glycoside and analyze side-effect during treatment. Methods:156 patients with hand eczema were enrolled in study.The patient group was divided into two groups(group A and group B) in open control-placebo clinical trial.In group A,80 patients were treated with Tripterygium Glycoside only,and in group B,76 patients were treated with irradiating NB-UVB and oral tripterygium glycoside.Therapy effect was evaluated afte...