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Case report of male child with elevated lipoprotein (a) leading to acute ischemic stroke
Authors:Patrick M. Moriarty  Heather Tennant  Nandhini Sehar  Lauryn Denney  Paola Luna  Francesca Perez‐Marques  Apurva Panchal  Michael Abraham  John Leever
Affiliation:1. Division of Clinical Pharmacology, University of Kansas Medical Center, Kansas City, Kansas, USA;2. Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA;3. Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas, USA;4. Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, USA;5. Department of Radiology, University of Kansas Medical Center, Kansas City, Kansas, USA
Abstract:
Acute ischemic stroke (AIS) in children is rare with almost 40% diagnosed as cryptogenic. One possible mechanism associated with AIS is an elevated Lipoprotein (a) [Lp(a)] level. Here, we discuss the case of an 11‐year old boy who presented with multiple thrombotic strokes secondary to elevated Lp(a), which was identified as the only risk factor and immediately treated with lipoprotein apheresis (LA). Eighteen months post‐AIS, he is still receiving LA treatments and has made remarkable progress in his recovery without another cerebrovascular event.
Keywords:acute ischemic stroke  lipoprotein (a)  lipoprotein apheresis  multiple thrombotic strokes  pediatric stroke
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