Cardiac resynchronization therapy improves left ventricular remodeling and function compared with right ventricular pacing in patients with atrioventricular block |
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| Authors: | Dasheng Lu Hao Zhang Hongxiang Zhang |
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| Affiliation: | 1.Department of Cardiology,The Second Affiliated Hospital of Wannan Medical College,Wuhu,China;2.Vascular Diseases Research Center of Wannan Medical College,Wuhu,China;3.Department of Cardiology,The Affiliated Hospital of Yangzhou University,Yangzhou,China |
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| Abstract: | Right ventricular pacing (RVP) exerts a detrimental effect on left ventricular (LV) remodeling. In patients with atrioventricular block (AVB) that require ventricular pacing, the effect of biventricular pacing (BiVP) versus RVP on LV remodeling and function has not been comprehensively assessed in a meta-analysis. Electric databases MEDLINE and Cochrane Library were retrieved for randomized controlled trials (RCT) comparing RVP and BiVP in patients with AVB. Data on left ventricular ejection fraction (LVEF) and LV volumes were analyzed, stratified by different time points. Eleven RCTs were included in the final analysis. There was a significant reduction of LV end-systolic volume in BiVP compared with RVP, at 3, 6, 12, and 24 months follow-up (P?
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