62例年轻妇女宫颈癌患者的临床研究及预后研究

目的探讨62例年轻妇女宫颈癌患者的临床特征和预后。方法入选2007年2月～2009年8月在某院妇产科住院治疗的62例年轻妇女患者,搜集患者的临床资料并对其进行随访。结果 62例患者中,46例表现为接触性阴道流血,占74.2%;白带异常者6例,占9.7%;不规则阴道流血、流液者7例,占11.3%;无明显症状、常规体检发现者3例,占4.8%。62例年轻妇女宫颈癌患者中,病理类型为鳞癌者48例,占77.4%;表现为腺癌者10例,占16.1%;腺鳞癌者3例,占4.8%;其他类型者1例,占1.7%。分析发现,62例年轻妇女宫颈癌患者HPV感染率为100%,其中HPV16阳性者46例,占74.2%;HPV18阳性者16例,占25.8%。术后随访6～36平均(23.4±6.2)个月,5例(8.1%)患者在术后出现复发,经化疗或放疗治疗后,患者出现好转,其中1例患者在术后2年死亡;其余患者均未出现复发。健在患者对目前的生活质量均较满意。结论年轻妇女宫颈癌患者的主要的临床表现为接触性阴道流血,采取以手术为主的治疗手段能显著改善患者的预后。

Study on the clinical presentation and prognosis of 62 young cases with cervical carcinoma in women

OBJECTIVE To investigate clinical presentation and prognosis of 62 young cases with cervical carcinoma.METHODS A total of 62 young cases with cervical carcinoma were selected in 2007 February-2009 August method in the Department of Gynecology and Obstetrics,the clinical information of 62 young cases were collected,and all of them were followed-up.RESULTS Among 62 patients,46 patients presented contact vaginal bleeding,accounted for 74.2%;6 cases showed abnormal leucorrhea,accounted for 9.7%;7 cases showed irregular vaginal bleeding and fluid,,accounted for 11.3%;3 patients showed no obvious symptoms by conventional medical examination,accounted for 4.8%.62 young cases with cervical carcinoma,and 48 patients showed pathological types of squamous cell carcinoma,accounted for 77.4%;10 cases were performed with adenocarcinoma,accounted for 16.1%;3 cases showed adenocarcinoma,accounted for 4.8%;1 case showed other type,and accounted for 1.7%.A total of 62 young cases with cervical carcinoma,and patients with HPV infection rate was 100%,46 cases showed HPV16 positive,and accounted for 74.2%;16 cases showed HPV18 positive,and accounted for 25.8%.The postoperative follow-up was 6 ~ 36 average(23.4 + 6.2)months,5(8.1%)patients showed recurrence in the postoperative.After chemotherapy or radiotherapy,patients improved,1 patients died after operation for 2 years;The remaining patients had no recurrence.On the current living patients quality of life were satisfactory.CONCLUSION Young women with cervical cancer showed the clinical manifestations of contact vaginal bleeding,and operation therapy can significantly improve the prognosis of the patients.