宿主猪乙脑病毒感染情况与人群发病关系的探讨

目的了解乙脑宿主猪乙脑病毒感染强度、感染时间分布和人群发病的关系,为乙脑防制提供科学依据。方法在国家级乙脑监测点桂平市、北流市和靖西县各选择10～12头2～3月龄的仔猪作为观察对象,编号标记,持续追踪观察5个月,每月上、中、下旬采集一次猪血清,采用酶联免疫法(ELISA)进行乙脑抗体IgG检测,阳性计为感染猪。结果 5月上旬开始出现阳性感染猪,阳性率为18.75%,随着乙脑流行季节的到来,猪的感染率逐渐增高,7月下旬达76.67%。人群的发病强度与宿主猪的感染分布一致,桂平市猪感染的时间出现早,阳性率高,病例出现的时间也早,病例数多,靖西县和北流市猪感染率低,病例数少。4～6月份人群发病曲线随着宿主感染率的上升而上升,7月份后人群发病与猪感染率呈反向分布,猪的自然感染出现时间比人间感染出现时间早3～4周。结论乙脑的发病与当地宿主猪感染情况密切相关,开展宿主猪监测可以预测人间乙脑流行强度和发病高峰时间,早期做好防控准备。

Study on the relationship between pigs JE virus infection and population incidence

OBJECTIVE To understand the host of JE virus infection in pigs,and its intensity,infection time distribution and the relationship,so as to provide a scientific basis for the control of JE.METHODS In the national sites of JE Guiping,Beiliu and Jingxi County,10-12 two or three months old pigs were selected as the observed object,the number sign,keep track of observed five months,monthly,and three times serum were collected by enzyme-linked immunosorbent assay(ELISA)for detection of JE antibody IgG positive as infected pigs.RESULTS Positive pigs were showed in early May of swine,and the positive rate was 18.75%.With the coming of JE epidemic season,pig infection rate was gradually increased to 76.67% in late July.The incidence of crowd intensity distribution was in line with the infection rate of host pigs.The infection time of pigs infection in Guiping occurred earlier with the high positive rate,and the number of cases also occurred earlier and showed more.The infection rate of Beiliu and Jingxi County showed low,and the number of cases showed less.From April to June,the host infection rates raised the population incidence curve of rising.The distribution was reversed in July,and the pigs naturally infected occurred about earlier 3 to 4 weeks than human infections.CONCLUSION The incidence of JE is closely related to the infection of local host pigs,monitoring of the host can predict the JE epidemic strength and peak time,and earlier prepared the foe prevention and control.