肝硬化门静脉高压合并胆囊结石的相关因素分析

目的探讨肝硬化门静脉高压合并胆囊结石的相关因素分析。方法选自某院收入的肝硬化门静脉高压患者共153例,患者根据是否有肝硬化门静脉高压合并胆囊结石分为两组,A组为肝硬化门静脉高压未合并胆囊结石组(116例),B组为肝硬化门静脉高压合并胆囊结石组(37例)。收集两组患者的性别、年龄、既往史、肝功能Child-Pugh评分等相关资料,数据进行统计学对比。结果对照组中E2为(13.26±4.37)pg/ml,观察组中E2为18.75±5.24,两组对比差异有统计学意义,P≤0.05。对照组的Child-pugh分级中的A级30例、B级67例,观察组的Child-pugh分级中的A级9例,B级15例,两组对比差异无统计学意义。对照组的Child-pugh分级中的C级21例(18.1%),观察者为13例(35.1%),两组对比差异有统计学意义,P≤0.05。结论肝功能Child-Pugh分级及雌激素水平(E2)为导致患者肝硬化门静脉高压合并胆囊结石的危险因素。

The related factors of cirrhosis portal hypertension with cholecystolithiasis

OBJECTIVE To investigate the related factors of cirrhosis portal hypertension with cholecystolithiasis.METHODS 153 cirrhosis portal hypertension cases were selected from our hospital.The patients were divided into two groups according whether with cholecystolithiasis.Group A was cirrhosis portal hypertension without cholecystolithiasis(116cases);Group B was cirrhosis portal hypertension with cholecystolithiasis(37cases).Collected two groups’ gender,age,past medical history,liver function Child-Pugh score and related materials.Tha data were statistically compared.RESULTS E2 was 13.26 +/-4.37 pg/ml in the control group,while was 18.75±5.24 pg/ml in the observation group,the result had a significant difference,P≤0.05.Liver Child-Pugh classification in the control group showed 30 cases of level A,67 cases of level B.Iin observation group,there were 9 cases of level A,15 cases of level B,the result did not have a significant difference.Liver Child-Pugh classification showed 21 cases of level C(18.1%)in the control group,13 cases(35.1%)in the observation group the result had a significant difference,P≤0.05.CONCLUSION Liver Child-Pugh classification and E2 are the risk factors of cirrhosis portal hypertension with cholecystolithiasis.