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化疗在晚期和复发性耐药性子宫内膜癌治疗中的作用
引用本文:李小平,王建六.化疗在晚期和复发性耐药性子宫内膜癌治疗中的作用[J].中国实用妇科与产科杂志,2015,31(3):216-220.
作者姓名:李小平  王建六
作者单位:作者单位:北京大学人民医院妇科,北京 100044
摘    要:晚期和复发性耐药性子宫内膜癌预后差,化疗在子宫内膜癌治疗中具有越来越重要的价值。新辅助化疗、序贯放化疗、分子靶向药物如贝伐单抗等是目前治疗子宫内膜癌的研究热点,紫杉醇联合卡铂和蒽环类药物联合铂类是一线化疗药物方案。复发性耐药性子宫内膜癌治疗尚无成熟方案,仍需大样本临床试验验证。

关 键 词:子宫内膜癌  化疗  耐药性  

The role of adjuvant chemotherapy in women with advanced or recurrent resistant endometrial cancer.
LI Xiao-ping;WANG Jian-liu.The role of adjuvant chemotherapy in women with advanced or recurrent resistant endometrial cancer.[J].Chinese Journal of Practical Gynecology and Obstetrics,2015,31(3):216-220.
Authors:LI Xiao-ping;WANG Jian-liu
Institution:Department of Obstetrics and Gynecology, Peking University People’s Hospital, Beijing 100044,China
Abstract:Abstract:The prognosis of advanced or recurrent resistant endometrial cancer is poor ,and the role of adjuvant chemotherapy has become more and more important.There are many new progress focusing on neoadjuvant chemotherapy, sequential multi-modality adjuvant chemotherapy and radiation, and molecular targeted therapy and so on.Now, paclitaxel combined with carboplatin and anthracycline plus platinum as first line chemotherapy regimen;however,there have been few studies about drug-resistant endometrial carcinoma, and still more samples are needed for clinical trial studies.
Keywords:endometrial cancer  chemotherapy  resistence  
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