| 用G-显带法和荧光原位杂交对医用诊断X射线工作者细胞遗传学分析和剂量重建 |
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| 引用本文： | 李进,王芹,唐卫生,孙元明,王知权. 用G-显带法和荧光原位杂交对医用诊断X射线工作者细胞遗传学分析和剂量重建[J]. 中华放射医学与防护杂志, 2003, 23(4): 260-262 |
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| 作者姓名： | 李进 王芹 唐卫生 孙元明 王知权 |
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| 作者单位： | 300192,天津,中国医学科学院中国协和医科大学放射医学研究所 |
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| 摘 要： | 目的 为了估算医用诊断X射线工作者的剂量。方法 对不同时期医用诊断x射线工作者分别采用G-显带和FISH法进行染色体畸变分析。结果 两种方法估算的剂量基本一致。结论 G-显带和FISH法是检测染色体易位的有效方法。
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| 关 键 词： | G-显带法 荧光原位杂交 医用诊断X射线工作者 细胞遗传学 剂量重建 染色体畸变 |
| 收稿时间： | 2002-12-25 |
| 修稿时间： | 2002-12-25 |
The study on cytogenetic analysis and dosimetry reconstruction for medical diagnostic X-ray workers using G-banding and fluorescence in situ hybridization |
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| LI Jin,WANG Qin,TANG Weisheng. The study on cytogenetic analysis and dosimetry reconstruction for medical diagnostic X-ray workers using G-banding and fluorescence in situ hybridization[J]. Chinese Journal of Radiological Medicine and Protection, 2003, 23(4): 260-262 |
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| Authors: | LI Jin WANG Qin TANG Weisheng |
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| Affiliation: | LI Jin,WANG Qin,TANG Weisheng,et al.Institute of Radiation Medicine,Chinese Academy of Medical Sciences and Peking Union Medical College,Tianjin 300192,China |
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| Abstract: | Objective To estimate the dose of medical diagnostic X-ray workers. Methods The chromosome aberrations were analyzed by G-banding or FISH in medical diagnostic X-ray workers with different calendar years of entry. Results The biological doses estimated by the two methods were in agreement with the doses evaluated by physical methods. Conclusion G-banding and FISH are effective ways to analyse the chromosome translocations. |
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| Keywords: | FISH G-banding X-ray workers Chromosomal aberrations |
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