胰岛素抵抗与认知功能障碍的相关性分析

目的探讨胰岛素抵抗与认知功能障碍的临床相关性。方法采用国际通用的简易智力状况量表(MMSE)对30例胰岛素抵抗患者(试验组)及50例非胰岛素抵抗者(对照组)进行认知功能评定,按照两组的MMSE结果进行统计分析胰岛素抵抗与认知功能障碍的临床相关性。结果 30例胰岛素抵抗者(试验组)小学、中学、大学各文化程度组认知功能障碍分别为26.67%、16.67%、23.33%,合计为66.67%;50例非胰岛素抵抗者(对照组)分别为8%、10%、6%,合计为24%;前者各文化程度组认知功能障碍阳性百分比均高于后者,且差异有统计学意义(P<0.05)。结论胰岛素抵抗与认知功能障碍具有高度相关性,是认知功能障碍发生的高危因素。

Correlation analysis of insulin resistance and cognitive impairment

Objective To investigate clinical relevant of insulin resistance and cognitive impairment. Methods In according to internationally Mini-mental state examination (MMSE), 30 patients with insulin resistance (test group) and 50 non-insulin-resisters (control group) for cognitive function were evaluated, and insulin cognitive dysfunction in resistance and clinical relevance were statistically analyzed according to two groups MMSE results. Results 30 cases of insulin resisters (test group) of primary, secondary,...