中西医结合治疗慢性肺源性心脏病急性加重期的疗效

目的探讨中西医结合治疗慢性肺源性心脏病急性加重期的临床疗效。方法将50例慢性肺源性心脏病急性加重期的患者按不同的治疗方法分为2组：治疗组（30例）和对照组（20例）。2组患者均采用常规的治疗，包括改善通气、解除支气管痉挛、祛痰、强心、利尿及纠正水、电解质平衡等。在此基础上，治疗组加用中药治疗。观察2组患者治疗前后心功能【左心室射血分数（LVEF）、每搏出量（SV）、心输出量（co）、心脏排血指数（CI）]、肺功能【第一秒用力呼出量（FEVl）、用力肺活量（FVC）、FEVl／FVC比值1改善及动脉血气分析（pH、PaO：、SaO：、PaCO：）、临床疗效的情况。结果治疗组总有效率明显高于对照组（P〈0．05）。对照组治疗后LVEF、SV、CO、CI、pH、Pa02、Sa02、PaC02均较治疗前明显改善（均P〈O．05），治疗组治疗后LVEF、SV、CO、CI、FEVl、FVC、FEVl／FVC比值、pH、Pa02、Sa02、PaC02均较治疗前明显改善（均P〈0．05），治疗组治疗后LVEF、SV、CO、CI、FEVl、FVC、FEVl／FVC比值、pH、Pa02、Sa02、PaC02均较对照组明显改善（均P〈O．05）。结论中西医结合治疗慢性肺源性心脏病急性加重期可明显改善患者的心、肺功能，无明显的不良反应，是一种治疗慢性肺源性心脏病急性加重期较理想的方法。

Integrated Traditional Chinese and Western Medicine for Acute Exacerbations of Chronic Pulmonary Heart Disease

Objective To investigate the clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of acute exacerbations of chronic pulmonary heart disease. Methods Fifty patients with acute exacerbations of chronic pulmonary heart disease were divided into two groups： treatment group （n=30） and control group （n=20）. All patients were given conventional treatment, incl- uding improving ventilation,relieving bronchospasm,strengthening cardiac function,expectorant, diuresis and correcting water and electrolyte balance. On this basis,the treatment group was treated with traditional Chinese medicine. Left ventricular ejection fraction （LVEF）,stroke volume （SV）,cardiac output （CO）,cardiac index （CI）,forced expiratory volume in 1 second （FEV1）,forced vital capacity （FVC）,FEV1/FVC ratio,pH,PaOE, SaO2 and PaCO2 were measured and clinical curative effect was observed in both groups. Results The total effective rate in treatment group was obviously higher than that in control group （P〈0.05）. After treatment,LVEF,SV,CO,CI,pH,PaOE, SaO2 and PaCO2 were signific- antly improved in control group, and LVEF,SV,CO,CI,FEV1,FVC, FEV1/FVC ratio, pH,PaO2,SaO2 and PaCO2 were significantly improved in treatment group （all P〈0.05）. Compared with control group, these pulmonary heart disease.