| 纳米银溶液的稳定性研究 |
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| 引用本文： | 魏欣欣,李明春,马守栋.纳米银溶液的稳定性研究[J].中国医院药学杂志,2016,36(16):1355-1358. |
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| 作者姓名： | 魏欣欣 李明春 马守栋 |
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| 作者单位： | 1. 青岛大学药学院, 山东 青岛 266021;
2. 中国人民解放军第401医院药剂科, 山东 青岛 266071 |
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| 基金项目： | 国家重大新药创制科技重大专项资助项目（编号：2008ZXJ09004-045） |
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| 摘 要： | 目的： 考察自制纳米银溶液的稳定性。方法： 以纳米银溶液的外观性状、紫外最大吸收波长、纳米银粒径、纳米银含量为考察指标，考察了温度、光线、pH等对稳定性的影响，并进行了长期稳定性试验。结果： 冷冻、强光、低pH值可使纳米银稳定性降低，室温下可稳定至少2年。结论： 纳米银溶液对强光、冷冻、酸不稳定，对热较稳定。纳米银溶液应避光、避冻，中性或弱碱条件下存放。
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| 关 键 词： | 纳米银溶液 稳定性 温度 光照 pH |
| 收稿时间： | 2015-12-18 |
Study on stability of nano silver solution |
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| WEI Xin-xin,LI Ming-chun,MA Shou-dong.Study on stability of nano silver solution[J].Chinese Journal of Hospital Pharmacy,2016,36(16):1355-1358. |
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| Authors: | WEI Xin-xin LI Ming-chun MA Shou-dong |
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| Institution: | 1. Pharmacy College, Qingdao University, Shandong Qingdao 266021, China;
2. No. 401 Hospital of PLA, Shandong Qingdao 266071, China |
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| Abstract: | OBJECTIVE To examine stability of homemade nano silver solution.METHODS Appearance,maximum absorption wavelength of ultraviolet, grain size and silver content were used as test items to study influence of temperature,light and pH values on stability of nano silver solution.Long term stability experiment was also performed.RESULTS Stability of nano silver solution can be decreased under circumstances of freeze,strong light and low pH.It can remain stable at room temperature for at least two years.CONCLUSION Nano silver solution is unstable to strong light,freezing and acid,and relatively stable to heat.It should be stored under neutral or weak alkaline conditions,and avoid light and freezing. |
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| Keywords: | nano silver solution stability temperature light pH |
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