药物经济学成本-效果在临床路径给药方案中的作用探究

目的:探究药物经济学成本-效果评价方法在临床路径给药方案的实践应用。正确认识药物经济学评价方法对临床路径的建立和应用的重要意义。方法:采用回顾法对2013年1月-2014年12月入住呼吸科第一诊断为"社区获得性肺炎"的患者。其中实施前(路径前组)100例,实施后药师参与(路径后组)100例,比较2组在给药方案药物费用、住院总费用、住院时间、药占比(药物费用/住院总费用)、抗菌药物占比(抗菌药物费用/住院药物费用)、检查费用、治疗效果、安全性等方面的指标。结果:2组患者在药物费用、住院总费用、成本-效果、住院时间方面统计学上有显著性差异(P<0.05),在治疗效果、安全性、检查费、药占比、抗菌药物占比方面无显著性差异(P>0.05)。结论:药师应用药物经济学成本-效果评价方法,协同医师制订给药方案,规范了合理用药,降低了药品费用和住院总费用,同时缩短了住院时间,节约了医疗资源,减轻了个人和社会负担,提高了医疗质量和患者满意度。

Role of pharmacoeconomics cost-effectiveness in clinical pathway dosage regimen

OBJECTIVE To explore pharmacoeconomics cost-effectiveness evaluation method in practice of clinical pathway dosage regimen, correctly understand significance of pharmacoeconomics evaluation method on establishment and application of clinical pathway. METHODS Retrospective method was applied to review patients with diagnosis of "community-acquired pneumonia" in our hospital from January 2013 to December 2014.These patients were divided into two groups, each included 100 patients. Pharmacists only joined therapeutic regimen in one group. Different indicators were compared between two groups, including drug dosage regimen, total hospitalization expenses, hospital days, drug cost ratio(drug cost/total cost in hospital), medication cost proportion of anti-infective drugs(anti-infective drugs/drug cost), inspection fees, therapeutic effects, safety, etc. RESULTS The two groups had significant differences(P<0.05) in drug cost, total hospitalization expenses, cost-effectiveness, hospital days, but not in therapeutic effects, safety, inspection fees, drug cost ratio, medication cost proportion of anti-infective drugs. CONCLUSION Pharmacists can apply pharmacoeconomics cost-effectiveness evaluation method, collaborate with physicians for establishing dosage regimen, which can standardize reasonable use of drugs, reduce drug expenses and hospitalization cost, decrease hospital days, save medical resources, reduce burdens on individual patients and the society, and improve medical quality and patient satisfaction.