纯钛等离子涂层圆柱状骨内种植体与周围骨界面的三维结构分析

目的:通过组织形态学的方法评价和分析纯钛等离子涂层圆柱状骨内种植体与周围骨界面的三维结构情况。方法:选择2只成年雄性比格犬,拔除双侧下颌第二、第四前磨牙,自行愈合3个月,植入纯钛等离子涂层圆柱状种植体,共8枚。3个月后处死动物,取下包含种植体的下颌骨,固定后用自动磨片机切片、染色、拍照数字化后输入计算机构建三维结构模型并分析。 结果:种植体平均骨接触率(bone contact ratio,BCR)为(64.5±5.3)%,最高在舌侧和上部,最低在近远中和底部。平均骨体积率(bone volume ratio, BVR)为(68.9±4.4)%,最佳在舌侧150~225 μm带和上部,最差在近远中0~75 μm带和底部。 结论:纯钛等离子涂层圆柱状骨内种植体与周围骨界面的三维结构能清晰的构建出来,二者能形成良好的结合,特别是在皮质骨致密的舌侧和上部。

Evaluation of Three-dimensional Structure of Bone around Pure Titanium Plasma-sprayed Cylindrical Endosseous Implants.

Objective: To evaluate and analyze three-dimensional structure of bone around the pure titanium plasma-sprayed cylindrical endosseous implants by histomorphometric method. Methods: Bilateral mandibular teeth (P2 and P4) of two healthy adult beagle dogs were extracted. After three months, pure titanium plasma-sprayed cylindrical endosseous implants were implanted. Three months later, the dogs were sacrificed and the mandible were harvested, fixed, sliced, stained, photographed and digitized. Data were imported into computer to construct three-dimensional model and analyzed. Results: The average bone contact ratio(BCR) of the implant was (64.5±5.3)%, peaked at lingual direction and upper portion, bottomed at mesial or distal direction and bottom portion. The average BVR was (68.9±4.4)%, peaked at lingual 150-225μm zone and upper portion, bottomed at mesial or distal 0-75μm zone and bottom portion. Conclusion: The three-dimensional structure of bone around pure titanium plasma-sprayed cylindrical endosseous implants can be established. Implants can achieve good osseointegration, especially at lingual and upper portion with dense cortical bone.