| 非特异性免疫治疗对射频消融术后肝细胞癌患者免疫功能的影响 |
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| 引用本文： | 蒋居毅, 刘天奇. 非特异性免疫治疗对射频消融术后肝细胞癌患者免疫功能的影响[J]. 分子影像学杂志, 2017, 40(1): 51-53. doi: 10.3969/j.issn.1674-4500.2017.01.15 |
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| 作者姓名： | 蒋居毅 刘天奇 |
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| 作者单位： | 1.广西壮族自治区灵山县人民医院肝胆外科，广西 钦州 535400;;2.广西壮族自治区人民医院肝胆腺体外科，广西 南宁 530021 |
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| 基金项目： | 广西科学研究与技术开发计划项目桂科攻1355005-3-15 |
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| 摘 要： | 目的探讨非特异性免疫治疗对射频消融术后肝细胞癌患者免疫功能的影响。方法采用流式细胞仪检测分析43例肝细胞癌患者治疗前和行射频消融术并接受非特异性免疫治疗后，外周血中CD4+T细胞、CD8+T细胞、NK细胞比例以及CD4+/CD8+值。结果行射频消融术并接受非特异性免疫治疗后患者外周血中的CD4+T细胞、NK细胞比例及CD4+/CD8+值均显著高于治疗前（P < 0.05），同时治疗后患者外周血中CD8+T细胞比例显著低于治疗前（P < 0.05）。结论非特异性免疫治疗可提高射频消融后肝细胞癌患者的免疫功能。
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| 关 键 词： | 肝细胞癌 射频消融 免疫治疗 免疫功能 |
| 收稿时间： | 2016-10-26 |
Effect of non-specific immune treatment on immunity of Patient with hepatocellular carcinoma after radiofrequency ablation |
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| Juyi JIANG, Tianqi LIU. Effect of non-specific immune treatment on immunity of Patient with hepatocellular carcinoma after radiofrequency ablation[J]. Journal of Molecular Imaging, 2017, 40(1): 51-53. doi: 10.3969/j.issn.1674-4500.2017.01.15 |
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| Authors: | Juyi JIANG Tianqi LIU |
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| Affiliation: | 1. Department of Hepatobiliary Surgery, 1Lingshan People's Hospital of Guangxi Zhuang Autonomous Region, Qinzhou 535400, China;;2. 2 the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China |
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| Abstract: | ObjectiveTo investigate the effect of radiofrequency ablation combined sequential nonspecific immune treatment on patient with hepatic carcinoma.MethodsBefore and after the radiofrequency ablation combined sequential nonspecific immune treatment, the percentage of CD4+ T cells, CD8+ T cells and NK cells on peripheral blood were evaluated by flow cytometry.ResultsAfter the nonspecific immune treatment, the percentage of CD4 + T cells, NK cells and CD4+/CD8 + ratio were significantly higher than that without treatment and CD8+ was significantly decreased (P < 0.05).ConclusionNon-specific immune treatment can improve the immune function in HCC after RFA. |
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| Keywords: | liver cancer radiofrequency ablation immune treatment immune function |
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