基于有限元方法的中耳听骨链结构运动机理研究

目的运用中耳Micro-CT扫描数据进行三维重建，采用有限元方法对听骨链运动规律及鼓膜振动特性进行生物力学研究。 方法通过对比鼓膜凸、镫骨足板振幅实验数据验证模型，并进行频率响应分析及模态分析。 结果在不同频率下听骨链振动与转动均不一样，三块听小骨围绕一定的转动轴进行转动和摇摆运动，接近鼓膜凸处的锤骨柄做同相位转动和平动，镫骨足板做活塞平动。在频率1000 Hz下鼓膜整体弯曲变形局部高达2.32e-006 m，出现在环韧带附近；鼓膜凸最大变形约1.0e-007 m。鼓膜环韧带在声压激励下容易发生扭曲变形。鼓膜凸附近出现应力集中，最大应力约8.33e-004 MPa。 结论听骨链运动机理研究对人耳生命科学研究和临床手术均有一定的理论指导意义。

Structure movement mechanism for auditory ossicle chain of human middle ear based on finite element method

ObjectiveTo reconstruct the middle ear structure in three-dimensional by Micro-CT data, and explore the motion rule of chain ossicles and tympanic membrane vibration characteristics in biomechanical theory research by using the finite element method. MethodsThe model was verified correctly by comparing finite element simulation data with experimental data about the amplitude of tympanic membrane umbo and stapes footplate. The conclusion was drawn by frequency response analysis and modal analysis. Results(1) The vibration and rotation of ossicular chain were different under various frequencies. Three ossicles performed rotating and rocking motion around axis of rotation. Manubrium mallei close to tympanic membrane umbo performed in same phase rotation and translation. Stapes footplate performed translation like the piston. (2) At the frequency of 1000 Hz, the total bending deformation of tympanic membrane ran up to 2.32e-006 m, which appeared in annular ligament of tympanic membrane. The maximum deformation of the membrane tympani umbo was about 1.0e-007 m. Under the excitation of sound pressure, the annular ligament of tympanic membrane was prone to distortion. The stress concentration occurred in the vicinity of membrane tympani umbo.The maximum stress was 8.33e-004 MPa. ConclusionMotion of ossicular chain will provide theoretical guidance for life science research and clinical operation of human ears.