| 茶多酚清除氧自由基作用研究 |
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| 引用本文： | 杨成峰,陈学敏,王桂珍.茶多酚清除氧自由基作用研究[J].中国公共卫生学报,1996(2). |
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| 作者姓名： | 杨成峰 陈学敏 王桂珍 |
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| 作者单位： | 同济医科大学环境卫生学教研室 |
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| 摘 要： | 用Ｆｅｎｔｏｎ反应产生羟自由基（ＯＨ），用黄瞟吟／黄瞟吟氧化酶反应系统产生超氧阴离子自由基（Ｏ），研究了茶多酚对ＯＨ和Ｏ的清除作用．结果表明，分别向产生ＯＨ和Ｏ的反应系统加入茶多酚后，可使ＯＨ和Ｏ的产生量显著减少，且随茶多酚加入剂量的增加，ＯＨ和Ｏ产生量减少也越显著（Ｐ＜０．０５）。本研究结果提示，茶多酚对ＯＨ和Ｏ具有直接清除作用。茶多酚对氧自由基的直接清除作用可能是其抑制突变和抗氧化作用的分子生物学基础．
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| 关 键 词： | 茶多酚，羟自由基（OH），超氧阴离子自由基（O_2~－） |
Study on Oxygen Free Radical-scavenging Effect of Green Tea Polyphenols |
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| Authors: | Yang Chengfeng |
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| Institution: | Yang Chengfeng,et al., |
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| Abstract: | The scavenging effect of Green Tea Polyphenols (GTP)on hydroxyl radical(OH) produced by Fenton reaction and superoxide anion radical (O) produced by xanthine/xanthineoxidase (X/XO) system was studied. The results showed that outputs of of and OH were reduced significantly by adding GTP to Fenton reaction and X/XO system respectively. This results indicated that GTP had direct scavenging effect on O and OH, and the direct scavenging effect of GTP on oxygen radicals may be molecular biological basis of its anti-mutation and antioxidation effect. |
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| Keywords: | Green Tea Polyphenols(GTP) Hydroxyl radical(OH) Superoxide anion radical(O) |
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