| 幽门螺杆菌甲硝唑耐药与细菌定植密度的研究 |
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| 引用本文： | 虎月燕,张瑜,李桂萍,周曾芬,蒋海燕,张磊.幽门螺杆菌甲硝唑耐药与细菌定植密度的研究[J].昆明医学院学报,2004,25(3):19-21. |
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| 作者姓名： | 虎月燕 张瑜 李桂萍 周曾芬 蒋海燕 张磊 |
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| 作者单位： | 昆明医学院第一附属医院消化内科,昆明,650032 |
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| 摘 要： | 目的：研究H.pylori对甲硝唑耐药与细菌定植密度问的关系．方法：用E-test方法检测109株H.pylori菌株对甲硝唑的敏感性；胃粘膜活检标本经Warthing-Starry染色后观察评定H.pylori定植密度．结果：109株H.pylori菌株的甲硝唑耐药率为67．89％；H.pylori定植密度的不同等级在H.pylori菌株甲硝唑耐药率上无显著性差异．结论：H.pylori对甲硝唑的敏感性与细菌定植密度无关．
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| 关 键 词： | 甲硝唑 细菌定植 耐药率 幽门螺杆菌 胃粘膜活检 敏感性 菌株 定植密度 显著性差异 等级 |
| 文章编号： | 1003-4706(2004)03-0019-03 |
| 修稿时间： | 2003年11月5日 |
Study on Metronidazole Resistance and Colonization Density of Helicobacter Pylori |
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| HU Yue-yan,ZHANG Yu,LI Gui-ping,ZHOU Zeng-fen,JIANG Hai-yan,ZHANG Lei.Study on Metronidazole Resistance and Colonization Density of Helicobacter Pylori[J].Journal of Kunming Medical College,2004,25(3):19-21. |
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| Authors: | HU Yue-yan ZHANG Yu LI Gui-ping ZHOU Zeng-fen JIANG Hai-yan ZHANG Lei |
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| Abstract: | Objective: To study the relationship of metronidazole resistance and colonization density of H. Pylori. Methods: Testing metronidazole susceptibilities of 109 H. Pylori strains by the use of the Epsilometer test (E-test); analyzing colonization density of H. Pylori in the gastric biopsy specimens by Warthing-starry stain. Results: In 109 H. Pylori strains, metronidazole resistant rate was 67.89%. There was no significant difference in the metronidazole resistant rate and colonization density of H. Pylori. Conclusion: There was no relation between metronidazole resistant rate and colonization density of H. Pylori. |
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| Keywords: | Helicobacter pylori Meteonidazole Resistance Colonization density |
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