| 血管内皮生长因子(VEGF)治疗冠心病的现状 |
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| 引用本文： | 陆传新,赵峰,林晓耘,程心培.血管内皮生长因子(VEGF)治疗冠心病的现状[J].心血管病学进展,2003,24(6):410-413. |
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| 作者姓名： | 陆传新 赵峰 林晓耘 程心培 |
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| 作者单位： | 解放军第四一一医院心内科,上海,200081 |
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| 摘 要： | 回顾1998年2月至2001年11月VEGF或其基因治疗严重冠心痛139例的方法、结果、副作用和安全性。绝大多数患者术中术后无明显并发症，术后其心绞痛发作频率、程度、持续时间均有明显改善，心肌灌注显像和冠脉造影等亦有明显改善。VEGF或其基因治疗严重冠心痛安全有效，但仍有一些问题需进一步研究。
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| 关 键 词： | 血管内皮生长因子 VEGF 治疗 冠心病 心绞痛 副作用 |
| 文章编号： | 1004-3934(2003)06-0410-03 |
| 修稿时间： | 2002年8月28日 |
Current Status of Vascular Endothelial Growth Factor(VEGF)in the Management of Coronary Heart Disease |
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| LU Chuan xin,ZHAO Feng,LIN Xiao yun,CHEN Xin pei.Current Status of Vascular Endothelial Growth Factor(VEGF)in the Management of Coronary Heart Disease[J].Advances in Cardiovascular Diseases,2003,24(6):410-413. |
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| Authors: | LU Chuan xin ZHAO Feng LIN Xiao yun CHEN Xin pei |
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| Abstract: | Methods,results,side effects and safety of VEGF or its gene therapy was reviewed in 139 patients with serve coronary heart disease from Feb 1998 to Nov 2001.Most patients have no complication intra or postoperation,their angina pectoris reduced in the frequency,grade,duration.Myocardial perfusion and coronary angiography showed the marked improvements in those subjects.VEGF or its gene therapy can be performed safely and efficaciously in serve coronary heart disease,but there are some problems needed to be studied. |
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| Keywords: | Growth factor Endothelial cell Coronary heart disease Therapy |
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