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脑脊液中肿瘤坏死因子测定对颅内感染的诊断价值
引用本文:吴若芬,李莉,刘菊年. 脑脊液中肿瘤坏死因子测定对颅内感染的诊断价值[J]. 陕西医学杂志, 2004, 33(1): 72-73
作者姓名:吴若芬  李莉  刘菊年
作者单位:宁夏医学院附属医院中心实验室,银川,750004
摘    要:目的 :了解脑脊液中肿瘤坏死因子 ( TNF)检测对颅内感染的诊断意义。方法 :对 60例不同病因的脑膜炎患者脑脊液 ( CSF)中肿瘤坏死因子 ( TNF- α)含量进行了测定。结果 :化脓性脑膜炎患者 CSF中 TNF- α含量较病毒性脑膜炎患者及正常对照组均有显著增高 ( P<0 .0 1 ) ,而病毒性脑膜炎患者 CSF中 TNF- α含量与正常组比较无明显差异 ( P>0 .0 5 )。结论 :CSF中 TNF- α检测可作为常规鉴别细菌性与非细菌性脑膜炎的指标

关 键 词:脑膜炎/诊断  脑膜炎/脑脊髓液  @肿瘤坏死因子

Diagnostic value of determination of tumor necrosis factor in CSF fof intracranial infection
Central Laboration,The Affiliated Hospital of Ningxia Medical College. Diagnostic value of determination of tumor necrosis factor in CSF fof intracranial infection[J]. Shaanxi Medical Journal, 2004, 33(1): 72-73
Authors:Central Laboration  The Affiliated Hospital of Ningxia Medical College
Affiliation:Yinchuan 750004
Abstract:Objective:To know the diaqnostic value of determination of tumor necrosis factor in CSF for the intracranial infection.Methods:The content of TNF-α in CSF was measured in 60 patieats with meningitis induced by various pathogeny.Results:Compared with the sufferers of viral meningitis group and the control group,the TNF-α content in CSF of sufferers with suppurate meningitis was increased distinctly (P<0.01), but there were no distinct differences (P>0.05) be tween the content of TNT-α in CSF of the sufferers of viral meningitis group and the control group.Conclusion:The determination of TNF-α in CSF can be used as a discriminating guideline between bacterial and non-bacterial meningitis.
Keywords:Meningitis/diagnosis Meningitis/cerebrospinal fluid(CSF) @TNF-α
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