| 抗坏血酸片剂稳定性的动力学研究 |
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| 引用本文： | 邓树海,栾本君,王立福,何仁杰,吕学苏. 抗坏血酸片剂稳定性的动力学研究[J]. 山东大学学报(医学版), 1994, 0(1) |
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| 作者姓名： | 邓树海 栾本君 王立福 何仁杰 吕学苏 |
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| 作者单位： | Dept. of Pharmiaceutics，Shandong Medical University |
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| 摘 要： | 用化学动力学（经典恒温）法和分光光度法，探讨了抗坏血酸片剂恒温加速实验的含量变化规律。结果表明，抗坏血酸片剂热解反应界于零级与一级动力学之间，偏属一级动力学。求得热解反应活化能为１９．９７ｋｃａｌ·ｍｏｌ－１，Ｔ０。为７．６７年，Ｔ０．９为１．１７年。
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| 关 键 词： | 化学动力学；分光光度测定法；Weibull分布模型法；抗坏血酸 |
CHEMICAL DYNAMICS STUDY ON THE STABILITY OF ASCORBIC ACID |
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| Deng Shuhai,et al. CHEMICAL DYNAMICS STUDY ON THE STABILITY OF ASCORBIC ACID[J]. Journal of Shandong University:Health Sciences, 1994, 0(1) |
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| Authors: | Deng Shuhai et al |
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| Abstract: | On the basis of chemical dynamic method (classical consistant temperature) and spectrophotometry, the content changes of ascorbic acid in tabula by accelerated experiment at consistant temperature were carried out.The results showed that the thermolysis process of ascorbic acid was between Zero and first-order chemical dynamic process and near to Zero-order.E= 19.93kcal. mol-1, T0.5=7.67Y, T0.9=1.17Y. |
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| Keywords: | Chemical dynamics Spectrophotometry Weibull's Distribution model Ascorbic acid |
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