凯时治疗糖尿病周围神经病变的临床观察

目的:观察凯时治疗糖尿病周围神经病变的临床疗效。方法:对确诊为糖尿病合并周围神经病变的69例患者随机分为治疗组和对照组两组。治疗组35例给予Lipo-PGE1治疗,10μg/d,共两周;对照组34例,给予维生素B110 mg/d、维生素B12500μg/d治疗,共两周,对其疗效进行比较。结果:治疗组用Lipo-PGE1治疗两周后,患者自觉症状和体征有明显改善,与对照组比较有显著性差异(P<0.01)。尺神经和腓神经MNCV及SNCV,治疗组前后比较有明显增加(P<0.01),对照组治疗前后比较有增加(P<0.05),治疗组与对照组比较明显增加(P<0.01),均有显著性意义。治疗组治疗过程中未出现严重副反应。结论:Lipo-PGE1是治疗糖尿病周围神经病变有效且安全的药物。

Clinical Observation of Effect of Lipo-PGE1 in treatment of Diabetic Peripheral neuropathy

Objective To observation the clinical effect of Lipo-PGE_1 in treatment of diabetic peripheral neuropathy.Methods 69 patients with DPN were divided into 2 groups,they were given the medicine of Lipo-PGE_110μg/d,or combined Vit B_1 10 mg/d and Vit B_(12) 500 μg/d,both for two weeks,and comparaed the clinical effect of the two groups in in treatment of diabetic peripheral neuropathy.Results The improvement of DPN symptoms and signs or never conduction speeds of the treatment group were obviously better than the contrast group(P<0.01).No obvious adverse drug reactions were observed.Conclusion LipoPGE_1 is an effective and safe drug in treatment of diabetic peripheral neuropathy.