| 雷公藤甲素的研究进展 |
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| 引用本文： | 刘明星,董静,杨亚江杨祥良,徐辉碧. 雷公藤甲素的研究进展[J]. 中国中药杂志, 2005, 30(3): 170-174 |
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| 作者姓名： | 刘明星 董静 杨亚江杨祥良 徐辉碧 |
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| 作者单位： | 华中科技大学,药物研究所,湖北,武汉,430074 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 查阅有关雷公藤甲素近10年来国内外的文献资料,选取具有较大应用价值及学术意义的内容,按雷公藤甲素的药理、药代学、毒理、临床应用及其半合成等几个方面分别介绍,拟对雷公藤甲素有一个全面的认识。雷公藤及雷公藤甲素是目前我国中药现代化研究的热点,鉴于它们的两面性(生物活性及毒性),利用现代高科技手段,开发高效低毒的新剂型是一项非常有意义的工作。
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| 关 键 词： | 雷公藤甲素 雷公藤 研究进展 |
| 文章编号： | 1001-5302(2005)03-0170-05 |
| 收稿时间： | 2003-05-10 |
Progress in research on triptolide |
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| LIU Ming-xing;DONG Jing;YANG Ya-jiang;YANG Xiang-liang;XU Hui-bi. Progress in research on triptolide[J]. China Journal of Chinese Materia Medica, 2005, 30(3): 170-174 |
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| Authors: | LIU Ming-xing DONG Jing YANG Ya-jiang YANG Xiang-liang XU Hui-bi |
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| Affiliation: | The Research Institute of Pharmaceutics, Huazhong University of Science and Technology, Wuhan 430074, China. |
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| Abstract: | To further understand triptolide, this paper has introduced the pharmacology, pharmacokinetics, toxicity, the clinic application and semi-synthesis of triptolide on basis of importanct and significant contents of reference which have been consulted in the past twents years. Presently triptolide and Tripterygium wilfordii have been a hot spot of modernization of Chinese traditional medicine. It is very important to develop a new dosage form of high effect and low toxicity by making use of advanced technology according to its characteristics. |
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| Keywords: | triptolide Tripterygium wilfordii research progress |
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