| 重楼对宫颈癌细胞钙信号的影响 |
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| 引用本文： | 高冬,高永琳,白平. 重楼对宫颈癌细胞钙信号的影响[J]. 福建中医学院学报, 2003, 13(4): 26-28 |
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| 作者姓名： | 高冬 高永琳 白平 |
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| 作者单位： | 1. 福建中医学院现代医学部,福建,福州,350003
2. 福建医科大学生化与分子生物学系,福建,福州,350004 |
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| 基金项目： | 福建省卫生厅青年基金资助项目 ( 3 2 0 2 1980 2 1) |
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| 摘 要： | 为探讨重楼对宫颈癌(Hela)细胞钙信号的影响及其抗癌作用机理。利用荧光染料Fura-2在细胞内能与游离钙结合，在一定波长光的激发下可发出荧光的特性，根据荧光的强度来检测游离钙浓度的变化，结果显示重楼可提高细胞内游离钙的浓度。
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| 关 键 词： | 重楼 宫颈癌 游离钙 浓度检测 瘤细胞 细胞增殖 植物药 |
| 文章编号： | 1004-5627(2003)04-0026-03 |
| 修稿时间： | 2003-04-21 |
Influence of Rhizoma Paridis on Calcium Messenger System in Hela Cells |
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| GAO Dong+,GAO Yong lin+,BAI Ping+. Influence of Rhizoma Paridis on Calcium Messenger System in Hela Cells[J]. Journal of Fujian College of Traditional Chinese Medicine, 2003, 13(4): 26-28 |
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| Authors: | GAO Dong+ GAO Yong lin+ BAI Ping+ |
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| Affiliation: | GAO Dong+1,GAO Yong lin+2,BAI Ping+1 |
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| Abstract: | To study the influence of rhizoma paridis(RP)on calcium messenger system in Hela cells and its mechanism of anticancer,the characteristics that fluorochrome Fura 2 could combine with free Ca+{2+} and give out of fluorescence under some wavelength light stimulation was used,and then the changes of free Ca+{2+} were determined according to intensity of fluorescence.The results showed that RP could stimulate the in flow of extracellular Ca+{2+},and then improve the cytoplasmatic free Ca+{2+} density. |
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| Keywords: | rhizoma paridis Hela cell free Ca+{2+} influence |
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