某院儿科住院患儿抗菌药物使用状况分析

目的了解儿科住院患儿抗菌药物应用情况,促进临床合理用药。方法收集该院儿科2012年1～12月出院病历1 269份,分析抗菌药物使用状况。结果 1 269份病历中使用抗菌药物1 132例次（89.2%）,其中单联使用708例次（62.6%,708/1 132）,二联使用289例次（25.5%,289/1 132）,三联使用14例次（1.2%,14/1 132）;预防性使用121例次（10.7%,121/1 132）。排序前10位的抗菌药物使用频次最高者依次为头孢唑肟钠（64.3%,728/1 132）、青霉素（46.8%,530/1 132）、阿奇霉素（36.7%,416/1 132）,抗菌药物使用种类较合理。结论重视抗菌药物的临床应用管理,开展用药监测,严格考核,加强宣教,将对临床合理用药发挥很大作用。

Antibiotics usage analysis in pediatric inpatients

Objective To understand application information of antibiotics in pediatric inpatients,in order to promote ra-tional clinical usage. Methods A total of 1 269 medical records of pediatrics department in the hospital from January to December 2012 were collected to analyze the situation of antibiotics usage. Results In 1 269 records,antibiotics were used in 1 132 cases （89.2%）,induding 708 cases for single use （62.6%,708/1 132）,289 for combination of two antibiotics （25.5%,289/1 132）,14 for three antibiotics（1.2%,14/1 132）,and 121 for preventive use（10.7%,121/1 132）. The antibiotics which were most frequently used were：ceftizoxime （64.3%,728/1 132）,penicillin （46.8%,530/1 132） and azithromycin （416/1 132）. The application of an-tibiotics were reasonable. Conclusion The arragement of clinical application,monitoring,evaluation and education of the antibi-otics play a significant role in clinical rational use.