|
|||||
|
|
Use of the COOH Portion of the Nucleocapsid Protein in an Antigen-Capturing Enzyme-Linked Immunosorbent Assay for Specific and Sensitive Detection of Severe Acute Respiratory Syndrome Coronavirus |
|
| Authors: | Maofeng Qiu Jin Wang Hongxia Wang Zeliang Chen Erhei Dai Zhaobiao Guo Xiaoyi Wang Xin Pang Baoxing Fan Jie Wen Jian Wang Ruifu Yang |
| Abstract: | Antibody detection with a recombinant COOH portion of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid (N) protein, N13 (amino acids 221 to 422), was demonstrated to be more specific and sensitive than that with the full-length N protein, and an N13-based antigen-capturing enzyme-linked immunosorbent assay providing a convenient and specific test for serodiagnosis and epidemiological study of SARS was developed. |
| Keywords: | |