Weight gain in early pregnancy and risk of gestational diabetes mellitus among Latinas |
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Authors: | T.A. Moore Simas M.E. Waring K. Callaghan K. Leung M. Ward Harvey A. Buabbud L. Chasan-Taber |
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Affiliation: | 1. Department of Obstetrics & Gynecology, University of Massachusetts Medical School/UMass Memorial Health Care, Worcester, MA 01605, United States;2. Department of Pediatrics, University of Massachusetts Medical School, Worcester, MA 01605, United States;3. Division of Epidemiology of Chronic Diseases and Vulnerable Populations, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01605, United States;4. 401 Arnold House, Department of Biostatistics & Epidemiology, School of Public Health & Health Sciences, University of Massachusetts, 715, North Pleasant Street, Amherst, MA 01003, United States |
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Abstract: | AimTo evaluate the association between gestational weight gain (GWG) in early pregnancy and incidence of abnormal glucose tolerance (AGT) and gestational diabetes mellitus (GDM) among Latinas.MethodsWe conducted a retrospective cohort study of 2039 Latinas using pooled data from two medical centres in Massachusetts. Gestational weights were abstracted from medical records and GWG was categorized as low, appropriate and excessive according to 2009 Institute of Medicine Guidelines. Diagnosis of AGT and GDM was confirmed by study obstetricians.ResultsA total of 143 women (7.0%) were diagnosed with GDM and 354 (17.4%) with AGT. After adjusting for age and study site, women with low GWG up to the time of GDM screen had a lower odds of GDM (OR: 0.51, 95% CI: 0.29–0.92). Among overweight women, women with excessive first-trimester GWG had 2-fold higher odds of AGT (OR: 1.96, 95% CI: 1.17–3.30) and GDM (OR: 2.07, 95% CI: 1.04–4.12) compared to those with appropriate GWG; however, these findings were not significant among normal weight or obese women.ConclusionAmong Latinas, low GWG up to the time of GDM screen was associated with lower odds of AGT and GDM, while excessive GWG among overweight women was associated with higher odds. Findings highlight need for interventions in early pregnancy to help women meet GWG guidelines and to moderate GWG among overweight Latinas. |
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Keywords: | Gestational diabetes Latina Pregnancy Weight gain |
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