| 天然与细胞培养竹节参的抗炎、镇痛作用研究 |
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| 引用本文： | 刘玉萍,王金萍,郭志刚,徐娟.天然与细胞培养竹节参的抗炎、镇痛作用研究[J].华北国防医药,2008,20(3):65-66. |
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| 作者姓名： | 刘玉萍 王金萍 郭志刚 徐娟 |
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| 作者单位： | [1]北京军区政治部第一干休所,北京100088 [2]北京军区总医院药理科,北京100700 [3]清华大学化工系,北京100084 |
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| 摘 要： | 目的:对比研究天然竹节参和植物细胞培养竹节参的抗炎和镇痛活性,确定细胞培养竹节参的活性成分.方法:以二甲苯致小鼠耳肿胀为急性炎症模型,以小鼠醋酸扭体实验为止痛模型,分别对天然竹节参,细胞培养竹节参及细胞培养竹节参的分离产物总皂苷、多糖等成分进行抗炎和镇痛试验.结果:细胞培养竹节参中、高剂量组对二甲苯致小鼠耳肿胀的影响与对照组比较,差异有显著性和非常显著性统计学意义(P<0.05,P<0.01);天然竹节参组及细胞培养竹节参中、高剂量组对醋酸致小鼠扭体反应的影响与对照组比较,差异有显著性及非常显著性统计学意义(P<0.05,P<0.01);竹节参分离产物总皂苷中、高剂量组对二甲苯致小鼠耳肿胀的影响与对照组比较,差异有显著性统计学意义(P<0.05);多糖组及总皂苷中、高剂量组对醋酸致小鼠扭体反应扭体次数的影响与对照组比较,差异有显著性及非常显著性统计学意义(P<0.05,P<0.01).结论:细胞培养竹节参与野生天然竹节参的药用价值相当.
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| 关 键 词： | 竹节参 细胞培养 竹节参 天然 抗炎 止痛 小鼠 |
A Study of Natural and Cell Culture Panax Japonicus on Anti-inflammatory and Analgesia |
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| LIU Yu-ping,WANG Jin-ping,GUO Zhi-gang,XU Juan.A Study of Natural and Cell Culture Panax Japonicus on Anti-inflammatory and Analgesia[J].Medical Journal of Beijing Military Region,2008,20(3):65-66. |
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| Authors: | LIU Yu-ping WANG Jin-ping GUO Zhi-gang XU Juan |
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| Institution: | LIU Yu-ping1,WANG Jin-ping2,GUO Zhi-gang3,XU Juan2(1.The 1st Retired Officers\' Center of Beijing Military Area,Beijing 100088,China,2.Department of Pharmacology,General Hospital of Beijing Military Area,Beijing 100700,3.Department of Chemical Engineering,Qinghua University,Beijing 100084,China) |
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| Abstract: | Objective:To compare the activity of natural and cell culture Panax japonicus on anti-inflammatory and analgesia and determine the active components in cell culture Panax japonicus.Methods:The natural and cell culture Panax japonicus,general saponin and polysaccharide were studied using xylene as acute inflaminnatory model for mice ear engorgement and analgesia model for mice writhing test.Results:Compared with the control group,medium and high dosage cell culture Panax japonicus significantly lessened the ... |
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| Keywords: | Panax japonicus cell culture natural Anti-inflammatory Analgesia Mice |
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