PET-CT在乳腺癌诊断中的应用价值

乳腺癌是当今大多数国家妇女最常见的恶性肿瘤。在过去的数十年中,正电子发射体层显像(PET)的应用极大地提高了乳腺肿瘤的临床诊治率。然而由于PET对肿瘤病灶缺乏准确的解剖定位而使18F-氟代脱氧葡萄糖(18F-FDG) PET临床应用的准确性受到限制。PET-CT的完美结合使对肿瘤的解剖定位和诊断的敏感性及特异性得到了明显的提高。本文着重介绍PET-CT在乳腺癌治疗后再分期、疗效观察、术前分期和放疗计划拟定中的应用价值。

The application value of PET-CT in the diagnosis of breast cancer

Breast cancer is the most common malignancy in women in most of countries. During the past decades, the application of PET with 18F-fluoro-2-deoxy-D-glocuse (18F-FDG) has remarkably improved the managemant of breast cancer. Nevertheless, due to anatomical localisation of 18F-FDG uptake was difficult, the clinical interpretation of 18F-FDG PET scan could not be exactly. A novel combined PET-CT system has largely improved the capacity of sensitivity and specificity in the diagnosis of breast cancer. In this artiacal we focus on the application value of PET-CT to breast cancer diagnosis, with respect to dissease re-staging, treatment monitoring, preoperative staging and radiotherapy planning.