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硫酸吗啡控释片对中晚期癌症患者镇痛效果的临床研究
引用本文:王忠明,刘桂荣,黄关宏,马建新,袁春銮,李秀翠.硫酸吗啡控释片对中晚期癌症患者镇痛效果的临床研究[J].中国医药科学,2011(5):25+82.
作者姓名:王忠明  刘桂荣  黄关宏  马建新  袁春銮  李秀翠
作者单位:江苏省连云港市第二人民医院肿瘤放疗科
摘    要:目的观察硫酸吗啡控释片对中晚期癌症患者疼痛的临床疗效。方法 56例中晚期癌症患者按量定时给药,每次30~180mg口服,(12~24)h∕次。结果 CR19例(33.9%),PR35例(62.5%),MR2例(3.6%),总有效CR+PR54例(96.4%)。结论硫酸吗啡控释片(美施康定)效果良好,服用方便,副作用小,可作为治疗癌痛的首选药物。

关 键 词:硫酸吗啡控释片(美施康定)  癌症疼痛  副作用

Clinical Effect Analysis on Morphine Sulfate Controlled-release Tablets on Medium-term and Advanced Cancerous Pain
WANG Zhongming,LIU Guirong,HUANG Guanhong,MA Jianxin,YUAN Chunluan,LI Xiucui.Clinical Effect Analysis on Morphine Sulfate Controlled-release Tablets on Medium-term and Advanced Cancerous Pain[J].China Medicine and Pharmacy,2011(5):25+82.
Authors:WANG Zhongming  LIU Guirong  HUANG Guanhong  MA Jianxin  YUAN Chunluan  LI Xiucui
Institution:Department of Radiotherapy, Lianyungang No.2 People’s Hospital in Jiangsu Province, Lianyungang 222023, China
Abstract:Objective To study the curative effect and side effect of morphine sulfate controlled-release tablets(meishikangding) on medium-term and advanced cancerous pain of patients. Methods Analysis on the treatment effect of paregorics on 56 cases of the patients with cancerous pain. The patients took meishikangding 30~180mg q12~24h po. Results The total effective rate was 96.4%(54/56), including 19(33.9%) cases of CR, 35(62.5%) cases of PR, 2(3.6%) cases of MR. The side effect included nausea, vertigo, constipation and somnolence. Conclusion Morphine sulfate controlled-release tablets(meishikangding) is effective to control medium-term and advanced cancerous pain, easy to take and less side effect. It can be used as drug of choice for treatment of medium-term and advanced cancerous pain.
Keywords:Morphine sulfate controlled-release tablets(meishikangding)  Cancerous pain  Side effect
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