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肿瘤病人红细胞的C3b受体活性观察
引用本文:蔡访勤,荆宇红,高元法,李逢志,熊沐霖. 肿瘤病人红细胞的C3b受体活性观察[J]. 郑州大学学报(医学版), 1986, 0(3)
作者姓名:蔡访勤  荆宇红  高元法  李逢志  熊沐霖
作者单位:河南省医学科学研究所(蔡访勤,荆宇红,高元法),河南省武装警察总医院(李逢志),河南医科大学一附院肿瘤科(熊沐霖)
摘    要:用ZC3b花环和IC-Z花环试验检测7例肝癌病人,29例肺癌病人,32例乳腺癌病人,12例淋巴肉瘤病人红细胞的C3b受体活性、及其表面粘附的免疫复合物。31例年龄相当的正常人作为对照。结果发现各组肿瘤病人红细胞的C3b受体活性明显低下,而红细胞表面粘附的免疫复合物明显增多。此项观察提示肝癌,肺癌,乳腺癌和淋巴肉瘤病人红细胞表面发生变化,特别是介导免疫粘附反应的C3b受体活性发生变化。

关 键 词:红细胞C3b受体  免疫复合物  肝癌  肺癌  乳癌腺  淋巴肉瘤

The observation on Red Cell C3b receptor activity of patients with cancer
Cai Fangqin,et al Henan Institute of Medical Sciences. The observation on Red Cell C3b receptor activity of patients with cancer[J]. Journal of Zhengzhou University: Med Sci, 1986, 0(3)
Authors:Cai Fangqin  et al Henan Institute of Medical Sciences
Abstract:The red cell C3b receptor activity and the quantity of immune-complex adherence to red cell surface of 7 patients with hepatoma, 29 with lung cancer, 32 with breast cancer, 12 with lymphosarcoma,and 31 age-match normal donors were compared by investigating the ability of ZC_3b-rosetts and IC-Z rosetts.In different group of patients with cancer the red cell C_3b receptor activity was significant lower, in contrast, the quantity of immune complex adherence to the surface of erythrocyte was significant increase when compared with age-match controls. These observation suggest that the hepatoma, lung cancer,breast cancer and lymphosarcoma are associated with surface changes of erythrocyte, especially those of the C_3b receptor which are responsible for immune adherence reaction.
Keywords:Red Cell C3b Receptor  Immune-complex   Hepatoma  Lung Cancer   Breast Cancer   Lymphosarcoma
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