54例重症严重急性呼吸综合征合并多器官损害的临床分析

目的 探讨重症严重急性呼吸综合征(SARS)合并多器官损害病例的临床特点。方法 回顾性分析2003年2月2日～4月5日收治的54例重症SARS病例的临床资料。结果 54例重症SARS患均出现全身炎症反应综合征(SIRS)，其中并发多器官损害49例(90．7％)，死亡12例(22．2％)，器官损害中以肺脏损害最常见，其次是肝、心、脑、肾和血液系统，其他器官受累较少。结论 重症SARS患容易出现多器官损害，病死率与脏器损害数有关。重症SARS并发多器官损害的治疗应该强调对多器官损害的早期发现和治疗，从而提高重症SARS的救治成功率。

Clinical analysis of 54 serious severe acute respiratory syndrome patients with multiple organ injury

Objective To study the clinical characteristics of the severe acute respiratory syndrome(SARS) patients who progressed into multiple organ injury Methods Retrospective analysis was performed on the clinical data of 54 severe SARS patients with multiple organ injury in our hospital Results In 54 SARS patients,systemic inflammatory response syndrome(SIRS) developed in all cases and multiple organ injury developed in 49 cases and the mortality of patients with multiple organ injury was 22 2% Among the involved organs,lungs were the most frequently involved organ,followed by liver,heart,brain,kidney and blood system The injury in other organs was rare Conclusions Serious SARS is predisposed to progress into multiple organ injury The mortality was correlated to the number of organs involved Recognization and treatment of multiple organ injury at early stage are critical with improve cure rate of serious SARS with multiple organ injury