| 雷公藤片治疗阿霉素肾病的实验研究 |
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| 引用本文： | 李玲,易著文,周汉昭,孙林. 雷公藤片治疗阿霉素肾病的实验研究[J]. 中南大学学报(医学版), 1994, 0(2) |
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| 作者姓名： | 李玲 易著文 周汉昭 孙林 |
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| 作者单位： | 第二附属医院儿科 |
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| 摘 要： | 应用阿霉素引起大鼠微小病变型肾病，观察雷公藤的治疗效果。结果显示，雷公藤可减少尿蛋白的排出，提高血清总蛋白，降低脂质过氧化物，促进肾小球上皮细胞足突结构恢复正常。文中对其机制进行了探讨。
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| 关 键 词： | 雷公藤；肾病综合征；脂质过氧化物；超氧化物歧化酶 |
EXPERIMENTAL STUDY OF TRIPTERGIUM WILFORDII HOOK IN THE TREATMENT OF ADRIAMYCIN NNEPHROSIS |
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| Li Linglin, Yi Zhuwen,Zhou Hanzhao,Sun Lin Departnient of Pediatrics,he Second Affiliated Hospital,Hunan Medical University. EXPERIMENTAL STUDY OF TRIPTERGIUM WILFORDII HOOK IN THE TREATMENT OF ADRIAMYCIN NNEPHROSIS[J]. Journal of Central South University. Medical sciences, 1994, 0(2) |
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| Authors: | Li Linglin Yi Zhuwen Zhou Hanzhao Sun Lin Departnient of Pediatrics he Second Affiliated Hospital Hunan Medical University |
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| Abstract: | This thesis reports the effect of the treatment with Triptergium Wilfordii Hook in ratswith minimal change nephrotic syndrome induced by adriamycin. It was found thatTriptergium Wilfordii Hook reduced the proteinuria significantly, increased total serum pro-tein and decreased lipidperoxide;the fusion of the glomerular epithelial foot processes was al-so improved.The results suggest that Triptergium Wilfordii Hook has the effect to scavengeoxygen free radical and to repair the ultrapathologic structure of the glomerular filter mem-brane. |
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| Keywords: | triptergium wilfordii hook nephrotic syndrome lipidperoxide super-oxde dismutase |
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