| 缝隙连接与心房颤动的折返机制 |
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| 引用本文： | 成永霞,钟国强.缝隙连接与心房颤动的折返机制[J].医学综述,2006,12(6):335-336. |
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| 作者姓名： | 成永霞 钟国强 |
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| 作者单位： | 广西医科大学第一附属医院心内科,南宁,530021 |
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| 摘 要： | 缝隙连接(GJ)由缝隙连接蛋白(Cx)构成,GJ作为细胞间的一种特殊通道介导着细胞间电和化学信号的传递,在维持电和机械耦联的正常进行以确保心肌协调收缩方面起着重要作用。GJ重构易致微折返形成,因而心房颤动容易产生和维持。
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| 关 键 词： | 心房颤动 缝隙连接 缝隙连接蛋白 折返 |
| 文章编号： | 1006-2084（2006）06-0335-02 |
| 收稿时间： | 2005-09-02 |
| 修稿时间： | 2006-01-07 |
Relationship Between Gap Junction and Reentrant Mechanism of Atrial Fibrillation |
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| CHENG Yong-xia,ZHONG Guo-qiang.Relationship Between Gap Junction and Reentrant Mechanism of Atrial Fibrillation[J].Medical Recapitulate,2006,12(6):335-336. |
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| Authors: | CHENG Yong-xia ZHONG Guo-qiang |
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| Institution: | Department of Cardiology, the First Affiliated Hospital of Guans~i Medical University, Nanning 530021, China |
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| Abstract: | Gap junction(GJ) composed of connexins,which is a special membrane pathway,mediates the transmission of electrical and chemical signals.It plays an important role in maintaining normal electromechanical coupling for synchronized contraction of myocardium.The remodeling of GJ is prone to form microreentry,which tends to cause and maintain the atrial fibrillation. |
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| Keywords: | Atrial fibrillation Gap junction Connexin Reentrant |
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