| 74例隆突型皮肤纤维肉瘤的治疗与预后分析 |
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| 引用本文： | 王修身,刘孟忠,刘慧.74例隆突型皮肤纤维肉瘤的治疗与预后分析[J].中德临床肿瘤学杂志,2006,5(6):454-457. |
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| 作者姓名： | 王修身 刘孟忠 刘慧 |
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| 作者单位： | [1]Department of Radiotherapy, Cancer Hospital of Henan Province, Zhengzhou 450008, China [2]Department of Radiotherapy, Cancer Hospital, Sun Yat-sen University, Guangzhou 510060, China |
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| 摘 要： | Objective： To study treatment and prognostic factor in 74 patients with dermatofibrosarcoma protuberans. Methods： From August 1990 to November 1999, 74 patients with dermatofibrosarcoma protuberans （DFSP） confirmed by pathology were treated in Cancer Hospital of Sun Yat-sen University. 72 cases were given wide excision and 2 cases were given local excision. All of 74 cases, 52 cases had surgical resection alone, and 22 cases had surgical resection combined with radiotherapy. Total dose of radiotherapy was 50-70 Gy. Results： The rate of recurrence was 36.1% for all patients. The 5-year recurrence-free survival （RFS） rate was 66%. The 5-year recurrence-free survival rates for resection alone and combined with radiotherapy were 58% and 90%, respectively （P=-0.0187）. The 5-year recurrence-free survival rates for positive microscopic margins and negative microscopic margins were 57% and 75%, respectively （P=0.0468）. Conclusion： Post-operation radiotherapy is an effective treatment to decrease the recurrence rate for the patients with positive microscope, or the patients without suitable surgical treatment.
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| 关 键 词： | 放射治疗法 病理学 DFSP 肿瘤学 |
| 收稿时间： | 2006-09-02 |
| 修稿时间： | 2006-11-15 |
The role of radiotherapy in 74 patients with dermatofibrosarcoma protuberans |
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| Xiushen Wang,Mengzhong Liu,Hui Liu,Nianji Cui.The role of radiotherapy in 74 patients with dermatofibrosarcoma protuberans[J].The Chinese-German Journal of Clinical Oncology,2006,5(6):454-457. |
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| Authors: | Xiushen Wang Mengzhong Liu Hui Liu Nianji Cui |
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| Institution: | (1) Department of Radiotherapy, Cancer Hospital of Henan Province, Zhengzhou, 450008, China;(2) Department of Radiotherapy, Cancer Hospital, Sun Yat-sen University, Guangzhou, 510060, China |
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| Abstract: | Objective:To study treatment and prognostic factor in 74 patients with dermatofibrosarcoma protuberans.Meth-ods:From August 1990 to November 1999,74 patients with dermatofibrosarcoma protuberans(DFSP)confirmed by pathology were treated in Cancer Hospital of Sun Yat-sen University.72 cases were given wide excision and 2 cases were given local exci-sion.All of 74 cases,52 cases had surgical resection alone,and 22 cases had surgical resection combined with radiotherapy.Total dose of radiotherapy was 50-70 Gy.Results:The rate of recurrence was 36.1% for all patients.The 5-year recurrence-free survival(RFS)rate was 66%.The 5-year recurrence-free survival rates for resection alone and combined with radiotherapy were 58% and 90%,respectively(P=0.0187).The 5-year recurrence-free survival rates for positive microscopic margins and negative microscopic margins were 57% and 75%,respectively(P=0.0468).Conclusion:Post-operation radiotherapy is an effective treatment to decrease the recurrence rate for the patients with positive microscope,or the patients without suitable surgical treatment. |
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| Keywords: | dermatofibrosarcoma protuberans (DFSP) radiotherapy wide excision |
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