涎腺癌肉瘤临床及病理分析

目的：探讨涎腺癌肉瘤的临床病理学特点及其鉴别诊断。方法：对3例涎腺癌肉瘤患者的临床资料进行回顾性研究并复习相关文献，对全部病例的组织学标本重新进行镜下观察。结果：涎腺癌肉瘤临床表现常为迅速增大的颜面部肿物并伴疼豢。光匀下组织学观察常可见肉瘤和癌两种成分并存，癌多为鳞状细胞癌和腺癌，肉瘤以骨或软骨肉瘤为主。结论：涎腺癌肉瘤的临床特点与涎腺其他恶性肿瘤较难区别，但涎腺癌肉瘤的恶性程度极高。

Clinicopathological analysis of salivary carcinosarcoma

Purpose To investigate the clinical and pathological characteristics and histogenesis of salivary carcinosarcoma. Methods The clinical materials of 3 cases with salivary carcinosarcoma were studied by retrospectively reviewing, including their clinical data and light microscopic examinations. Results Initial symptoms of salivary carcinosarcoma were ache and tumidness of face. Microscopically, the tumors were composed of both carcinoma and sarcomatous elements. Usually the carcinomatous element formed squamous cell carcinoma and adenocarcinoma. The sarcomatous element formed the osteosarcoma and chondroblastoma. Conclusions Salivary carcinosarcoma is easily confused with salivary carcinoma in clinical features. Because of its aggressive behavior and poor survival, salivary carcinosarcoma should be paid more attention to its diagnosis and management.