呼气负压技术在慢性阻塞性肺疾病患者中的应用

目的 探讨呼气负压技术在不能完成常规肺功能测定的慢性阻塞性肺疾病（COPD）患者中的临床应用价值。方法 采用呼气负压技术检测13例不能完成常规肺功能检查的COPD患者呼气流速受限。结果13例均能耐受呼气负压技术检测，无不良反应发生，12例有呼气流速受限，呼气流速受限评分5分法与MRC（medical research council）呼吸困难评分呈显著正相关，5分法呼气流速受限评分对呼吸困难有显著预测意义。结论 呼气负压技术是一种操作简单、非侵袭性、不需患者主动配合的肺功能检查方法，可在不能完成常规肺功能检查的患者中应用。

Clinical application of negative expiratory pressure technique in chronic obstructive pulmonary disease patients

Objective To explore the significance of negative expiratory pressure technique in detecting expiratory flow limitation in chronic obstructive pulmonary disease (COPD) patients. Methods Negative expiratory pressure technique was performed in 13 special COPD patients who did not accomplish routine pulmonary function tests. Results Negative expiratory pressure technique was executed successfully in 13 special COPD patients without any side-effects. Expiratory flow limitation was detected in 12 special COPD patients. 5-point expiratory flow limitation score was significantly correlated with Medical Research Council (MRC) dyspnea score, which was a predictor of dyspnea. Conclusions Negative expiratory pressure technique provides a test which is simple, rapid, noninvasive and does not require any initiative cooperation from the patients, it can be applied in special COPD patients who can not accomplish routine pulmonary function tests.