| TAO眼眶成纤维细胞上CCR1的表达 |
| |
| 引用本文： | Liu CL,Zhang XJ,Guo B,Yang JF,Luo QL. TAO眼眶成纤维细胞上CCR1的表达[J]. 四川大学学报(医学版), 2011, 42(5): 630-632 |
| |
| 作者姓名： | Liu CL Zhang XJ Guo B Yang JF Luo QL |
| |
| 作者单位： | 四川大学华西医院眼科,成都,610041 |
| |
| 基金项目： | 国家自然科学基金(批准号30371518); 四川省科技厅科技支撑项目(项目编号2009JY0007-1)资助 |
| |
| 摘 要： | 目的 研究趋化因子受体CCR1在甲状腺相关眼病(thyroid associated ophthalmopathy,TAO)的眼眶成纤维细胞(orbital fibroblasts,OFs)上的表达,探讨其在发病机制中的作用.方法 采用免疫组织化学SP法检测25例TAO患者和10例正常对照的眼眶组织中OFs上CCR1的...
|
| 关 键 词： | CCR1 甲状腺相关眼病 发病机制 成纤维细胞 免疫组化 |
Expression of CCR1 in the orbital fibroblasts with thyroid associated ophthalmopathy |
| |
| Liu Chun-Ling,Zhang Xue-Jin,Guo Bo,Yang Jun-Feng,Luo Qing-Li. Expression of CCR1 in the orbital fibroblasts with thyroid associated ophthalmopathy[J]. Journal of Sichuan University. Medical science edition, 2011, 42(5): 630-632 |
| |
| Authors: | Liu Chun-Ling Zhang Xue-Jin Guo Bo Yang Jun-Feng Luo Qing-Li |
| |
| Affiliation: | LIU Chun-ling,ZHANG Xue-jin,GUO Bo,YANG Jun-feng,LUO Qing-li.Department of Ophthalmology,West China Hospital,Sichuan University,Chengdu 610041,China |
| |
| Abstract: | Objective To investigate the expression of chemokine receptor(CCR1) in the orbital fibroblasts(OFs) with thyroid associated ophthalmopathy(TAO) and to explore the pathogenesis of TAO.Methods By immunohistochemistry,the expression of CCR1 was studied in 25 cases of TAO patientsand 10 normal control subjects and the correlation between CCR1 and GAS was analysed.Results The expression of CCR1 in the OFs with TAO was positive,but it was negative or weak positive in normal control subjects.The difference between... |
| |
| Keywords: | CCR1 Thyroid associated ophthalmopathy Pathogenesis Fibroblasts Immunohistochemistry |
| 本文献已被 CNKI 万方数据 PubMed 等数据库收录！ |
|
