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非小细胞肺癌中PGP9.5的表达与其神经内分泌分化关系的研究
引用本文:焉春华,王秋实,王宏伟,邵玉霞. 非小细胞肺癌中PGP9.5的表达与其神经内分泌分化关系的研究[J]. 哈尔滨医科大学学报, 2011, 45(4): 342-345
作者姓名:焉春华  王秋实  王宏伟  邵玉霞
作者单位:1. 哈尔滨医科大学附属第二医院呼吸内科
2. 胸外科,黑龙江哈尔滨,150081
摘    要:目的 探讨外科切除非小细胞肺癌(non-small cell lung cancer,NSCLC)中蛋白基因产物9.5( protein gene product 9.5,PGP9.5)表达的临床病理特征和意义及其与神经内分泌分化标记物神经烯醇化酶(neuron specific enolase,NSE)、突触素(sy...

关 键 词:肺肿瘤  神经内分泌分化  生物学特性  蛋白基因产物9.5

Relationship between expression of protein gene product 9.5 and neuroendocrine differentiation in non-small cell lung cancer
YAN Chun-hua,WANG Qiu-shi,WANG Hong-wei,SHAO Yu-xia. Relationship between expression of protein gene product 9.5 and neuroendocrine differentiation in non-small cell lung cancer[J]. Journal of Harbin Medical University, 2011, 45(4): 342-345
Authors:YAN Chun-hua  WANG Qiu-shi  WANG Hong-wei  SHAO Yu-xia
Affiliation:YAN Chun-hua1,WANG Qiu-shi2,WANG Hong-wei1,SHAO Yu-xia1(1.Department of Respiratory,2.Department of Thoracic Surgery,The Second Affiliated Hospital of Harbin Medical University,Harbin 150081,China)
Abstract:Objective To investigate the clinicopathologic features and the significance of protein gene product 9.5(PGP9.5) in surgically resected non-small cell lung cancer(NSCLC) and to determine the relationship between the expression of PGP9.5 and neuron specific enolase(NSE)and synaptophysin(SYN).Methods Immunohistochemical staining for PGP9.5,NSE and SYN was performed on paraffin embedded sections from 135 NSCLC patients who had been treated with complete curative surgery.The results of immunohistochemical stain...
Keywords:lung neoplasms  neuroendocrine differentiation  biological characteristics  protein gene product 9.5  
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