| 卡维地洛对高血压的降压作用及对胰岛素抵抗的影响 |
| |
| 引用本文： | 李志业,万大国. 卡维地洛对高血压的降压作用及对胰岛素抵抗的影响[J]. 中国临床药学杂志, 2007, 16(1): 53-54 |
| |
| 作者姓名： | 李志业 万大国 |
| |
| 作者单位： | 1. 郑州大学第二附属医院,药剂科,郑州,450014
2. 郑州大学第二附属医院,心内科,郑州,450014 |
| |
| 摘 要： | 目的探讨卡维地洛的降压作用及对胰岛素抵抗的影响。方法对58例高血压病Ⅰ期或Ⅱ期患者服用卡维地洛10 mg,bid,疗程为6 wk;治疗前后观察血压、空腹血糖(FBS)、血脂和胰岛素敏感性(ISI)的变化。结果服药前收缩压(158．3±13．5)mm Hg,舒张压(92．3±5．7)mm Hg;服药后收缩压(141．5±12．7)mm Hg,舒张压(81．8±6．4)mm Hg,服药前后比较(P< 0．05),治疗前后血糖、血脂无显著性改变(P>0．05),胰岛素敏感性增加(P<0．05)。结论卡维地洛能有效地降低收缩压和舒张压,能显著改善胰岛抵抗。
|
| 关 键 词： | 卡维地洛 高血压 胰岛素抵抗 |
| 文章编号： | 1007-4406（2007）01-0053-02 |
| 修稿时间： | 2005-09-21 |
Effect of carvedilol on blood pressure and insulin resistance in patients with hypertension |
| |
| LI Zhi-ye,WAN Da-guo. Effect of carvedilol on blood pressure and insulin resistance in patients with hypertension[J]. Chinese Journal of Clinical Pharmacy, 2007, 16(1): 53-54 |
| |
| Authors: | LI Zhi-ye WAN Da-guo |
| |
| Affiliation: | 1Department of Pharmacy,2Dertment of Cardiology, The Second Affiliated Hospital, Zhengzhou University , Zhengzhou 450014, China |
| |
| Abstract: | AIM To assess the impact of carvedilol on blood pressure and insulin resistance. METHODS Fifty-eight patients with hypertension I or II phase received carvedilol 10 mg,bid.Treatment lasted for 6 wk,and blood pressure, fasting blood sugar(FBS), serum lipid and insulin sensitive index(ISI) were observed before and after treatments. RESULTS Carvedilol could effectively control the patient systolic and diastolic pressure. FBS, serum lipid had not significantly changes before and after treatments, but ISI increased obviously. CONCLUSION Carvedilol could significantly control blood pressure and improve insulin resistance obviously. |
| |
| Keywords: | carvedilol hypertension insulin resistance |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
