临床分离的铜绿假单胞菌耐药性检测

目的了解医院临床分离的铜绿假单胞菌的耐药情况,为合理使用抗菌药提供参考依据。方法采用琼脂扩散试验法,对临床分离的263株铜绿假单胞菌的耐药性进行了检测。结果 263株铜绿假单胞菌有63.12%分离自病人呼吸道标本,有21.67%分离自病人的尿和胸腹水标本。临床分离的铜绿假单胞菌对妥布霉素等14种常用抗生素不同程度耐药,对哌拉西林.他唑巴坦、环丙沙星等8种抗生素耐药率达到59%~85%。结论临床分离的铜绿假单胞菌主要来自病人呼吸道标本,对临床常用抗生素不同程度耐药,且耐药性日趋严重,应加强抗生素应用管理。

RESISTANCE DETECTION OF CLINICAL ISOLATED Pseudomonas aeruginosa STRAINS

Objective To know drug resistance of the clinical isolated Pseudomonas aeruginosa and to provide reference for the rational use of antibiotics.Methods Agar diffusion test method was used to detect drug resistance of 263 clinical isolated P.aeruginosa strains.Results 63.12% of the 263 strains were separated from respiratory samples and 21.67% were separated from urine and pleural.The clinical isolated P.aeruginosa were different degrees of drug resistance to tobramycin and other 14 kinds of commonly used antibiotics.The rate of drug resistance was 59%-85% to eight different antibiotics including piperacillin-tazobactam,ciprofloxacin etc.Conclusions The clinical isolated P.aeruginosa were mainly from respiratory,which resistant to commonly used antibiotics with different degree.Antibiotic application management should be strengthened.