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412例药物致皮肤过敏反应及处置分析
引用本文:鲁涛,刘继勇. 412例药物致皮肤过敏反应及处置分析[J]. 实用药物与临床, 2011, 14(5): 412-414
作者姓名:鲁涛  刘继勇
作者单位:1. 南京市胸科医院药剂科,南京,210029
2. 第二军医大学长海医院药学部,上海,200433
摘    要:目的分析近3年文献报道的药物致皮肤过敏反应及其药物治疗方案。方法通过检索维普信息数据库、清华同方中国期刊网数据库、中国生物医学文献光盘数据库,统计近3年关于药物致皮肤过敏反应的文献资料,分析其药物治疗方案。结果 412例报告中,涉及中药7类,化学药品21类。中药注射剂和抗菌药物是引起皮肤过敏反应的主要药物。药物致皮肤过敏的临床表现以荨麻疹和斑丘疹最为常见,其治疗以抗组胺药、糖皮质激素、葡萄糖酸钙等联用为主。结论药物致皮肤过敏反应在临床上具有较高的发生率,其治疗方法较局限。应合理使用药物,减少药物致过敏反应的发生,同时,应开发使用方便、副作用小的新型抗过敏药物。

关 键 词:皮肤过敏反应  致敏药物  皮疹  抗过敏治疗  合理用药

Analysis of treatment of 412 patients with drug-induced cutaneous allergic diseases
LU Tao,LIU Ji-yong. Analysis of treatment of 412 patients with drug-induced cutaneous allergic diseases[J]. Practical Pharmacy and Clinical Remedies, 2011, 14(5): 412-414
Authors:LU Tao  LIU Ji-yong
Affiliation:LU Tao1,LIU Ji-yong2(1.Nanjing Chest Hospital,Nanjing 210029,China,2.Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China)
Abstract:Objective To analyze the drug-induced cutaneous allergic reaction and drug treatment program in articles for last 3 years retrospectively.Methods The articles about drug-induced cutaneous allergic reaction for last 3 years were searched from Cqvip.com,cnki.net and CBMdisc databases.Results 412 cases were found with 7 kinds of traditional Chinese medicine and 21 kinds of chemistry medicine.The main drugs that induce cutaneous allergic reaction were traditional Chinese medicine injection and antimicrobials,an...
Keywords:Cutaneous allergic reaction  Sensitizing drugs  Eruption  Anti-allergic therapy  Rational drug use  
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