| 优泌乐25联合二甲双胍治疗预混人胰岛素70/30血糖控制欠佳的2型糖尿病患者的疗效 |
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| 引用本文： | 杨颖,邓晨昕,高凌,张黎明,马计,肖婧,田源.优泌乐25联合二甲双胍治疗预混人胰岛素70/30血糖控制欠佳的2型糖尿病患者的疗效[J].实用药物与临床,2011,14(6):474-475. |
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| 作者姓名： | 杨颖 邓晨昕 高凌 张黎明 马计 肖婧 田源 |
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| 作者单位： | 襄阳市中心医院内分泌科,湖北襄阳,441021 |
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| 摘 要： | 目的研究2次/d预混人胰岛素70/30治疗血糖控制欠佳的2型糖尿病患者转用优泌乐25联合二甲双胍治疗的有效性和安全性。方法 2次/d注射预混人胰岛素70/30(联合或不联合口服降糖药)血糖控制欠佳的2型糖尿病患者54例,换用优泌乐25联合二甲双胍治疗。在治疗开始及12周分别记录空腹血糖、餐后2 h血糖、HbA1c(糖化血红蛋白)、体重指数及胰岛素剂量。结果治疗12周后,空腹血糖、餐后2 h血糖、HbA1c、体重指数及胰岛素剂量均较基线水平显著下降。出现低血糖12例。结论应用预混人胰岛素70/30治疗血糖控制欠佳的2型糖尿病患者,转用优泌乐25联合二甲双胍治疗后,其血糖可得到安全、有效的控制。
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| 关 键 词： | 糖尿病 优泌乐25 二甲双胍 |
Effect of insulin mix lispro 75/25 combined with metformin on inadequate glycemia control patients with type 2 diabetes treated with premixed insulin regimen |
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| YANG Ying,DENG Chen-xin,GAO Ling,ZHANG Li-ming,MA Ji,XIAO Jing,TAN Yuan.Effect of insulin mix lispro 75/25 combined with metformin on inadequate glycemia control patients with type 2 diabetes treated with premixed insulin regimen[J].Practical Pharmacy and Clinical Remedies,2011,14(6):474-475. |
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| Authors: | YANG Ying DENG Chen-xin GAO Ling ZHANG Li-ming MA Ji XIAO Jing TAN Yuan |
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| Institution: | YANG Ying,DENG Chen-xin,GAO Ling,ZHANG Li-ming,MA Ji,XIAO Jing,TIAN Yuan(Department of Endocrinology,Xiangyang Central Hospital,Xiangyang 441021,China) |
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| Abstract: | Objective To study the efficacy and safety of insulin mix lispro 75/25 combined with metformin on inadequately glycemia control patients with type 2 diabetes who have been treated with premixed insulin regimen.Methods 54 patients with type 2 diabetes mellitus taking premixed insulin were switch to insulin mix lispro 75/25 plus metformin due to the inadequate glycemia control.The fasting blood glucose(FBG),2-h post prandial blood glucose(2-hPBG),glycosylated haemoglobin(HbA1c),body mass index(BMI),insulin do... |
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| Keywords: | Diabetes mellitus Insulin mix lispro 75/25 Metformin |
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