| 丹参和半枝莲对丝裂霉素C诱发小鼠MN和SCE的防护作用 |
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| 引用本文： | 赵景春,高伟.丹参和半枝莲对丝裂霉素C诱发小鼠MN和SCE的防护作用[J].癌变．畸变．突变,1994,6(6):44-47. |
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| 作者姓名： | 赵景春 高伟 |
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| 作者单位： | 北京联合大学职技师院保健科学系遗传毒理教研室 |
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| 摘 要： | 本文以姊妹染色体交换（ＳＣＥ）和微核（ＭＮ）为指标，评价了中药丹参和半枝莲对丝裂霉素Ｃ（ＭＭｃ）诱发小鼠遗传物质损伤的影响，证实了两种中药本身并无诱变作用，提出了丹参，半枝莲具有抗ＭＭＣ诱发遗传物质损伤的作用。
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| 关 键 词： | 丹参 半枝莲 微核 SCE 中药 抗癌药 |
PROTECTIVE EFFECTS OF SALVIA MIL TIORRHIZA AND SCUTELLARIA BARBATA ON GENETIC
DAMAGE INDUCED BY MITO-MYCIN C(MMC) |
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| Abstract: | By using sister chromatid exchange(SCE)and mieronucleus(MN)as indexes,the
protective effects of Salvia miltiorrhiza and Scutellaria on genetic damage induced by MMC
was studied in Kunming mice strain.Results showed that the two Chinese medieines
themselves can not induce genetic damages but can significantly decrease SCE and MN
frequencies induced by MMC,respectively(P<0.01).The results indicated the Chinese medicines
could be anti-mut-agenesis. |
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| Keywords: | Salvia miltiorrhiza Scutellaria Micronucleus SCE Genetic damage |
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