A clinical observation of early short-term use of potent antibiotics in severely burned patients |
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| Authors: | RONG Xin-zhou ZHANG Wen-zhen REN Jia-liang ZHOU Wei-ming |
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| Institution: | Department of Burns, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China Department of Burns, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China Department of Burns, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China Department of Burns, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China |
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| Abstract: | Objective:To evaluatetheeffectof earlyandshort-termuseof potentantibioticsfollowingextensivesevere burninjury.Methods:Seventeenseverelyburnedpatientshospitalizedin thesameperiod(Nov.,1998to Oct.,2000)were dividedinto2groups.PatientsinGroup1(n=9)receivedearlytreatmentwithimipenumandamikacinfor5d,andthe sametreatmentin Group2(n=8)was discontinueduntilday15postburn.Thesurvivalrate,bloodbacterialculture,body temperatureand whitebloodcellandplateletcountswerecomparedbetweenthe2groups.Results:Allthe17patients survivedandallbloodbacterialcultureswerenegative.No significantdifferenceof bodytemperatureandwhitebloodcell andplateletcountsbetweenthe2groupswasobserved(P>0.05).Conclusion:Earlyuseof high-potencyantibioticsatshort treatmentcourseafterextensivesevereburniseffectiveto preventinfectionandreducethecost. |
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| Keywords: | burn injury infection antibiotics |
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